Patients with congenital bleeding disorders have an increased risk of bleeding from invasive dental and oral surgery procedures and require pre-treatment with factor concentrate
Block injections
Tooth extraction
Intubation
Factor concentrate should be given as near to the time of extraction as possible
Oral anti-fibrinolytic therapy is used for 7 days to allow healing of the mucous membrane and prevent re-bleeding following an extraction.
Routine cleanings do not require intervention therefore can be provided in a general dental practice
Successful management involves close collaboration between hematologists, hemophilia treatment centers (HTCs), and dentists
Celynda G. Tadlock, PharmD, MBA
Vice President, Pharmacy
Business Development
Aetna
Anderson JAM, et al. Br Dental J. 2013;215:497-504.