Inhibitor Management via Prophylaxis

• The bypassing agent prophylaxis regimen is intended to achieve the following objectives:
  

  –	Reduce the overall frequency of painful bleeds in the patient’s knees and other joints
  –	Allow for a 6 week course of PT three times weekly (on days when he gets his factor) to achieve better muscle strength and improved physical function
  –	Allow the patient to participate in more of his usual activities without experiencing a bleed
  –	Preserve the patient’s quality of life in terms of family and leisure activities which involve walking and using his arms
  –	Possibly slow the progression of joint deterioration by preventing bleeding in joints that still have good function, such as his elbows

 

Cindy Leissinger, MD Professor of Medicine, Pediatrics & Pathology Chief, Section of Hematology & Medical Oncology Tulane University School of Medicine	Soucie JM, et al. Blood. 2000;96(2):437-42.